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Grants.govALN 93.395RFA-OD-27-005

INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)

National Institutes of Health

Est. program funding: $3MCloses in 693 days· Jun 15, 2028

Summary

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this NOFO may not exceed five years. This NOFO provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33) of up to three years, although the total duration of the award may not exceed five years. This NOFO requires measurable R61 milestones.

Related documents

Geography
US
Award range
Amount not specified
Est. program funding
$3M
Cost share
Not required
Open date
May 13, 2026
Close date
Jun 15, 2028
Funding type
Grant
Expected awards
4
Opportunity type
Discretionary
Source
Grants.gov

Eligibility

NonprofitFor-profitGovernmentInstitution

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. | applicant types: Independent school districts; City or township governments; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public housing authorities/Indian housing authorities; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); State governments; Public and State controlled institutions of higher education; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification)

Categories

Economic DevelopmentEducationHealthInfrastructureHousing

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