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Grants.govALN 93.867RFA-OD-27-004

INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)

National Institutes of Health

Up to $500KCloses in 648 days· Jun 15, 2028

Summary

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

Related documents

Geography
US
Award range
Up to $500K
Est. program funding
$3M
Cost share
Not required
Open date
May 12, 2026
Close date
Jun 15, 2028
Funding type
Grant
Expected awards
4
Opportunity type
Discretionary
Source
Grants.gov

Eligibility

NonprofitFor-profitGovernmentInstitution

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. | applicant types: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Public and State controlled institutions of higher education; City or township governments; State governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Private institutions of higher education; Small businesses; County governments; Others (see text field entitled "Additional Information on Eligibility" for clarification)

Categories

Economic DevelopmentEducationHealthHousing

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