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Grants.govALN 93.279PAR-25-446

Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

National Institutes of Health

Up to $3MCloses in 715 days· Aug 21, 2028

Summary

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.

Related documents

Geography
US
Award range
Up to $3M
Cost share
Not required
Open date
Sep 10, 2025
Close date
Aug 21, 2028
Funding type
Cooperative agreement
Opportunity type
Discretionary
Source
Grants.gov

Eligibility

NonprofitFor-profitGovernmentInstitution

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession. | applicant types: State governments; Native American tribal governments (Federally recognized); Small businesses; Public housing authorities/Indian housing authorities; City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; For profit organizations other than small businesses; Independent school districts; Public and State controlled institutions of higher education

Categories

Economic DevelopmentEducationHealthHousing

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