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Grants.govALN 93.242RFA-MH-27-135

Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)

National Institutes of Health

Est. program funding: $5.5MCloses in 81 days· Oct 11, 2026

Summary

The purpose of this notice of funding opportunity (NOFO) is to elucidate the key components of the therapeutic effects of rapid-acting psychotropic interventional drugs (RAPIDs) by addressing the methodological challenges involved with these clinical trials. In addition, this NOFO seeks to advance understanding of how RAPIDs and adjunctive psychosocial interventions can be optimally delivered, monitored, and sustained over time to enhance effectiveness and generalizability. The NOFO will support studies designed to enhance the rigor of RAPID clinical trial design, which will ultimately increase the interpretability of the data and the generalizability of the results.

Related documents

Geography
US
Award range
Amount not specified
Est. program funding
$5.5M
Cost share
Not required
Open date
Apr 29, 2026
Close date
Oct 11, 2026
Funding type
Grant
Expected awards
5
Opportunity type
Discretionary
Source
Grants.gov

Eligibility

NonprofitFor-profitGovernmentInstitution

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. | applicant types: Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Small businesses; State governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Independent school districts; Private institutions of higher education; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification)

Categories

Economic DevelopmentEducationHealthHousing

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