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Grants.govALN 93.310RFA-RM-27-003

NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

National Institutes of Health

Est. program funding: $8MCloses in 42 days· Sep 3, 2026

Summary

The NIH Director"s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director"s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Related documents

Geography
US
Award range
Amount not specified
Est. program funding
$8M
Cost share
Not required
Open date
Jun 29, 2026
Close date
Sep 3, 2026
Funding type
Grant
Expected awards
7
Opportunity type
Discretionary
Source
Grants.gov

Eligibility

NonprofitFor-profitGovernmentInstitution

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. | applicant types: County governments; Independent school districts; State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities; Special district governments; Native American tribal governments (Federally recognized); For profit organizations other than small businesses

Categories

Economic DevelopmentEducationHealthInfrastructureHousing

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